buy Ambien (Zolpidem Tartrate)10mg Zolpidem tartrate as conventional tablets, oral spray, or sublingual tablets (Edluar) is used as a hypnotic agent in the short-term management of insomnia characterized by difficulties with sleep initiation. Because zolpidem has a short half-life, the drug may be of particular benefit in the initiation of sleep (i.e., decreasing sleep latency). In controlled clinical studies of 4-5 weeks’ duration, the drug reportedly has been effective in decreasing sleep latency for periods up to 35 days in duration.
Zolpidem tartrate as extended-release tablets is used in the management of insomnia characterized by difficulty with sleep onset or sleep maintenance. However, zolpidem tartrate extended-release tablets may not be an appropriate treatment choice for patients (men or women) with insomnia who need to drive or perform activities that require full alertness the next morning (see Cognitive and Psychomotor Impairment under Cautions: Precautions and Contraindications and also Next-day Impairment under Cautions: Nervous System Effects). In two 3-week, randomized, double-blind, placebo-controlled clinical trials in patients with chronic primary insomnia, zolpidem tartrate given as extended-release tablets improved sleep induction (as measured by latency to persistent sleep [LPS]) and sleep maintenance (as measured by wake time after sleep onset [WASO]).
In a 24-week, randomized, double-blind, placebo-controlled clinical trial in adults 18-64 years of age with chronic primary insomnia, zolpidem tartrate 12.5-mg extended-release tablets administered as needed 3-7 nights per week were superior to placebo on a patient-rated global impressions measure and on specific patient-reported parameters for sleep induction and maintenance; no substantial increase in frequency of drug use over time was observed.